This clinical will evaluate the safety, tolerability and early efficacy of pirenidone in patients with recurrent acute pancreatitis.
Patients 18 - 85 years of age
amylase or lipase values, or both, that are greater than 3 times the upper limit of normal values
characteristic cross-sectional imaging
typical upper abdominal pain according to the revised Atlanta classification28
Age < 18 or > 85 years.
Body weight > 200 kg.
Ongoing AP (in right clinical situation defined by pain>3, vomiting ≥once a week, fever or chills, not tolerating light diet) or diagnosis of AP in previous 30 days.
Diagnosis of chronic pancreatitis, one of the following
University of Alabama at Birmingham
Lead sponsor
Congressionally Directed Medical Research Programs
Collaborator