Feasibility Study for Fibroblast Autologous Skin Grafts
ConditionWounds and Injuries
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorJohns Hopkins University
About this trial
This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
Eligibility criteria
Qualifiers
May be male or female
Must be between 18 years and 65 years of age
In the opinion of the investigator, must be medically able to undergo the administration of study material determined by laboratory tests obtained within 7 days before baseline for which the investigator identified no clinically significant abnormality.
Be able to comprehend the informed consent document and provide consent for participation
Disqualifiers
Having received any investigational drug within 30 days prior to study entry
An allergy history to any study materials including local anesthetic, dimethyl sulfoxide, human albumin, or bovine constituents, or hetastarch
Pregnant, lactating, or trying to become pregnant
A history of keloid formation
Trial design
Treatments tested in this trial
- autologous skin fibroblasts
- Filler Product
Treatment groups
80 Participants
are divided into 1 treatment groupSponsors and collaborators
Johns Hopkins University
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborator
United States Department of Defense
Collaborator
Maryland Stem Cell Research Fund
Collaborator
Source ClinicalTrials.gov