Human Papillomavirus (HPV) Vaccination vs. Placebo for the Treatment of Refractory Cutaneous Warts

ConditionWarts
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorWestern Institute for Veterans Research

About this trial

This double-blinded clinical trial randomly assigns participants with refractory cutaneous warts to receive either treatment with the human papillomavirus (HPV) vaccine or a placebo to assess the efficacy of HPV vaccination for the treatment of refractory cutaneous warts.

Eligibility criteria

Qualifiers

Must be able to understand and provide written informed consent

Age 18 or older

Clinical diagnosis of cutaneous warts

Must have received prior treatment for cutaneous warts (such as curettage, cryotherapy, salicylic acid, intralesional Candida antigen injection, etc.)

Disqualifiers

Untreated cutaneous warts

Anogenital warts

Oral warts

Treatment for cutaneous warts in the past 4 weeks

Trial design

Treatments tested in this trial

  • Human Papillomavirus 9-valent Vaccine, Recombinant
  • Normal Saline

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Western Institute for Veterans Research

Lead sponsor

University of Utah

Collaborator

Merck Sharp & Dohme LLC

Collaborator