Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorFernando Bacal
About this trial
The goal of this study is to evaluate if hypertonic saline solution can prevent or attenuate acute kidney injury after heart transplantation in the early postoperative phase.
Eligibility criteria
Qualifiers
Hospitalized patients submitted to orthotopic heart transplantation (HT)
Disqualifiers
Requirement of renal replacement therapy at the time of HT
Requirement of extracorporeal membrane oxygenation (ECMO) before or immediately after HT
Severe peri-operative mechanical complications
Double transplant (e.g. heart-kidney or heart-lung)
Trial design
Treatments tested in this trial
- Sodium chloride solution 3,5%
- Sodium chloride solution 0,9%
Treatment groups
74 Participants
are divided into 2 treatment groupsSponsors and collaborators
Fernando Bacal
Lead sponsor
University of Sao Paulo General Hospital
Sponsor institution
Source ClinicalTrials.gov