Immunotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Louisville

About this trial

Compare the efficacy and tolerability of irreversible electroporation in combination with Nivolumab in patients with locally advanced pancreatic cancer.

Eligibility criteria

Qualifiers

≥ 18 years if age

Diagnosed with stage III pancreatic cancer

Tumor is measurable

Glomerular Filtration Rate > 60 m/L/min/1.73 m(2)

Disqualifiers

Participating in another clinical trial for the treatment of cancer at time of screening

Are pregnant or currently breast feeding

Have a cardiac pacemaker or Implantable Cardioverter Defibrillator implanted that cannot be deactivated during the procedure

Have non-removable implants with metal parts within 1 cm of the target lesion

Trial design

Treatments tested in this trial

  • Nivolumab
  • Irreversible Electroporation

Treatment groups

10 Participants
are divided into 1 treatment group

Sponsors and collaborators