Inguinal Node Sparing Radiotherapy For Patients With Early Stage Anal Cancer
ConditionAnal Canal Cancer
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorAHS Cancer Control Alberta
About this trial
The purpose of this study is to see whether avoiding preventative radiation to the groin in patients with normal sentinel node biopsy and PET-CT, is at least as effective treating cancer as giving preventative radiation to the groin for patients with anal canal cancer.
The investigators also want to know if avoiding radiation to the groin will cause fewer side effects and better quality of life
Eligibility criteria
Qualifiers
Participants capable of giving informed consent.
Patients must be 18 years of age or older.
Patient should have histologically proven primary squamous cell carcinoma.
Patients must have early AC, Stage T1-3 N0 M0.
Disqualifiers
T1N0 patients going for primary surgery
Prior radiation therapy to the pelvis.
Pregnancy or lactation.
Prior surgical treatment for anal cancer other than biopsy.
Trial design
Treatments tested in this trial
- chemo-radiation treatment
Treatment groups
45 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov