Iparomlimab and Tuvonralimab Injection (QL1706) Combined With Bevacizumab for Postoperative Adjuvant Therapy in Hepatocellular Carcinoma (HCC) With High Risk of Recurrence

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorThe Affiliated Hospital of Xuzhou Medical University

About this trial

Evaluation of the efficacy and safety of Iparomlimab and Tuvonralimab Injection (QL1706) in combination with bevacizumab for postoperative adjuvant treatment of HCC with high-risk recurrence risk

Eligibility criteria

Qualifiers

Voluntarily participate in this study and sign the informed consent form;

Age 18-100 years old, male or female;

Hepatocellular carcinoma confirmed by histopathology, cytology or imaging;

CNLC PHASE I-II;

Disqualifiers

It is known that there are fibrotic plate HCC, sarcomatoid HCC or mixed-type cholangiocarcinoma and HCC;

There is evidence of residual, recurrent or metastatic disease;

History of hepatic encephalopathy;

Previous receipt of allogeneic stem cell or solid organ transplantation, or on the waiting list for liver transplantation;

Trial design

Treatments tested in this trial

  • Iparomlimab and Tuvonralimab Injection (QL1706) plus bevacizumab

Treatment groups

60 Participants
are divided into 1 treatment group

Locations

This trial has no locations