IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia
ConditionLaparotomy
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of Iowa
About this trial
The purpose of this research study is to determine if the two common ways of administering additional opioids (morphine like substance, narcotic) with an epidural, either mixed in the epidural solution or given separately through the intravenous, are equally effective in controlling post-operative pain
Eligibility criteria
Qualifiers
Age including and between 18 to 85 years old
Planned open abdominal procedure with an incision that is or includes above the umbilicus, where epidural would normally be offered and epidural would be maintained for an average of 4 to 5 days
Patient has consented for an epidural
Patient is able to converse in English
Disqualifiers
Has a known contraindication for an epidural
Known mental or cognitive disability
History of chronic opioid use or substance abuse disorder
Pre-operative use of opioids
Trial design
Treatments tested in this trial
- Intravenous administered opioid
- Epidural administered opioid
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov