Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

ConditionsDescending Aortic Dissection Postoperative Pain Thoracoabdominal Aortic Aneurysm

Trial statusRecruiting

Trial phasePhase 2

Trial typeInterventional

Biological sexAll

Age18-90

SponsorSam Tyagi

About this trial

The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).

Eligibility criteria

Qualifiers

willing to give informed consent

scheduled for elective thoracic aorta repair or thoracoabdominal aortic repair

requires naloxone continuous infusion for spinal prophylaxis

Disqualifiers

allergy to ketamine, acetaminophen, or fentanyl

diagnosis of schizophrenia

history of hydrocephalus or central nervous system mass

incarcerated individuals

Trial design

Treatments tested in this trial

Saline
Ketamine

Treatment groups

30 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Sam Tyagi

Lead sponsor

University of Kentucky

Sponsor institution

Source ClinicalTrials.gov