L-Carnitine Protective Effect in Nephrotoxicity
ConditionNephrotoxicity
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorTanta University
About this trial
The goal of this clinical trial is to assess the possible reno-protective effect of L-carnitine against cisplatin-induced nephrotoxicity in patients receiving cisplatin-based chemotherapy. The main question it aims to answer is:
Does L-carnitine have the ability to protect the kidney against cisplatin-induced nephrotoxicity?
Eligibility criteria
Qualifiers
Male or female patients.
Newly diagnosed patients with cancer and with an indication for cisplatin - based chemotherapy.
Age between 18 and 75 years.
No serious cardiopulmonary comorbidity which could impair involvement in the study.
Disqualifiers
Pregnancy or lactation.
Metastasis to the central nervous system.
Psychiatric disorders.
Prior treatment with platinum derivatives.
Trial design
Treatments tested in this trial
- L-Carnitine Tartrate
- Placebo
Treatment groups
46 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov