The purpose of this research study is to determine if lattice radiation therapy (LRT) will provide better treatment for bulky (large) tumors than current standard of care radiotherapy.
Solid tumor malignancy with a clinical indication for radiation
Patients must have measurable disease
Target lesion(s) which are amenable to lattice therapy plan
When applicable, target lesion for radiation amenable to immobilization during delivery of radiotherapy
Patients receiving cytotoxic chemotherapy or known radiosensitizing agents within 5 days before or after lattice therapy.
Patients with hematologic malignancies including lymphoma and leukemia as well as primary or metastatic central nervous system (CNS) malignancies.
Patients with a history of conditions which predispose them to increased radiation toxicity
Patients with known contraindications to radiation therapy