Magnesium Sulfate in Addition to Bupivacaine in Ultrasound-guided Transmuscular Quadratus Lumborum Block for Post-Operative Analgesia After Total Hip Arthroplasty

Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorTanta University

About this trial

The aim of this clinical trial is to evaluate the efficacy of adding magnesium sulfate to bupivacaine in ultrasound-guided transmuscular quadratus lumborum block for postoperative analgesia in adult patients underdoing hip arthroplasty. The main questions it aims to answer are:

* Does Magnesium sulphate lower Pain score (VAS) postoperatively. * Does Magnesium sulphate lowerTotal opioid consumption postoperatively. and What side effects do participants have when taking Magnesium sulphate? Researchers will compare Magnesium sulphate to a placebo (a look-alike substance that contains no drug) to see if Magnesium sulphate works to lower pain score.

Participants will:

* Take with have ultrasound-guided transmuscular quadratus lumborum block after surgery using bupivacaine with Magnesium sulphate or with placebo * Followed up 48 hours postoperatively to monitor pain score or any reported side effect.

Eligibility criteria

Qualifiers

Age ≥ 18 years.

American Society of Anesthesiology (ASA) class I-III

Undergoing hip arthroplasty .

Disqualifiers

Patient refusal.

Body mass index (BMI) > 40 Kg/m2.

Allergy to local anesthetics or magnesium sulphate.

coexisting coagulopathy.

Trial design

Treatments tested in this trial

  • Bupivacaine + Magnesium sulfate
  • Bupivacaine + saline

Treatment groups

70 Participants
are divided into 2 treatment groups

Sponsors and collaborators