Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-89
SponsorVanderbilt University Medical Center

About this trial

Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and death. This randomized controlled trial will determine whether a pill containing healthy gut bacteria can increase the number good bacteria in the gut, lower levels of inflammation, and lower the risk of heart disease and death.

Eligibility criteria

Qualifiers

HIV infected

Disqualifiers

Not fluent in English

Trial design

Treatments tested in this trial

  • Probiotic
  • Placebo

Treatment groups

250 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Vanderbilt University Medical Center

Lead sponsor

University of Louisville

Collaborator

Boston University

Collaborator