About this trial
The number of women having an induction of labour is increasing and is currently used in 33% of pregnancies for a range of medical reasons. The majority of women are admitted to hospital to have their labour induced, using methods which are protracted and associated with a poor birth experience, making them both costly and unpopular. Further, current methods of outpatient induction are unsuitable, unsafe and/or have a poor acceptability. The COVID-19 pandemic has driven a reduction in the number of face-to-face interactions taking place across all areas of medicine. Proving the efficacy and safety of Mifepristone would significantly reduce pre-labour admission rates and hospital length of stay for pregnant women, who are at particularly higher risk of COVID-19, and reduce delivery costs.
Eligibility criteria
Qualifiers
Pregnant women between 36+5 and 41+5 weeks of gestation
Singleton pregnancy
Aged 18 years or older
Unfavourable cervix (Bishop Score less than or equal to 6)
Disqualifiers
Breech presentation
Early labour
Contraindication to vaginal birth (placenta praevia, transverse lie, known or suspected cephalo-pelvic disproportion or other factor contraindicated to vaginal birth in the opinion of the investigator)
Fetal growth restriction with oligohydramnios and/or abnormal Dopplers
Trial design
Treatments tested in this trial
- Mifepristone
- Placebo