Mucoadhesive Film With/without Acmella Oleracea & Triamcinolone Acetonide for Aphthous Ulcers

Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-50
SponsorKhon Kaen University

About this trial

The purpose of this study is to evaluate the effectiveness of mucoadhesive film with or without Acmella oleracea extract compared to standard treatment by using 0.1% triamcinolone acetonide in pain relief, promoting wound healing, healing time and satisfaction in 3 aspects included taste, product used and quality of life after using the product.

Eligibility criteria

Qualifiers

Healthy participants aged 18-50 years without any underlying diseases.

Participants are voluntary and have signed the informed consent.

Participants are literate.

Participants can follow the treatment guidelines and follow up.

Disqualifiers

Participants with allergies to herbal extracts, Acmella oleracea, or steroids.

Participants with chronic underlying diseases.

Participants with underlying diseases that may affect wound healing.

Participants receiving anti-analgesic drug, systemic steroids, antibiotics, hormones, NSAIDS, or any drugs that affect the oral mucosa.

Trial design

Treatments tested in this trial

  • mucoadhesive film with Acmella oleracea extract
  • Triamcinolone Acetonide 0.1% Oromucosal Paste
  • mucoadhesive film without Acmella oleracea extract

Treatment groups

72 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

Khon Kaen University

Lead sponsor

National Institute of Dental and Craniofacial Research (NIDCR)

Collaborator