About this trial
The purpose of this study is to evaluate the effectiveness of mucoadhesive film with or without Acmella oleracea extract compared to standard treatment by using 0.1% triamcinolone acetonide in pain relief, promoting wound healing, healing time and satisfaction in 3 aspects included taste, product used and quality of life after using the product.
Eligibility criteria
Qualifiers
Healthy participants aged 18-50 years without any underlying diseases.
Participants are voluntary and have signed the informed consent.
Participants are literate.
Participants can follow the treatment guidelines and follow up.
Disqualifiers
Participants with allergies to herbal extracts, Acmella oleracea, or steroids.
Participants with chronic underlying diseases.
Participants with underlying diseases that may affect wound healing.
Participants receiving anti-analgesic drug, systemic steroids, antibiotics, hormones, NSAIDS, or any drugs that affect the oral mucosa.
Trial design
Treatments tested in this trial
- mucoadhesive film with Acmella oleracea extract
- Triamcinolone Acetonide 0.1% Oromucosal Paste
- mucoadhesive film without Acmella oleracea extract
Treatment groups
Locations
Sponsors and collaborators
Khon Kaen University
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
Collaborator