Multimodal Magnetoencephalography and Electroencephalography Exploration of the Acute Effects of THC Exposure on Neural Noise and Information Transmission Within Working Memory Networks

ConditionTHC
Trial statusNot yet recruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age21-65
SponsorYale University

About this trial

The purpose of this study is to use non-invasive brain imaging methods (MEG and EEG) to characterize the effects of THC on brain activity during learning.

Eligibility criteria

Qualifiers

Cannabis use at least once in the past 12 months

No cannabis use during the course of the study confirmed with negative urine toxicology at screening and on each test day

Good physical and mental health

Disqualifiers

Cannabis naïve individuals

Lifetime or current medical, psychiatric or psychosocial disorders or history that is deemed unsuitable for participation in the study per PI discretion.

Positive pregnancy test, lactation, or refusal to practice birth control for the duration of the study and for two weeks following completion

Major current or recent stressors

Trial design

Treatments tested in this trial

  • THC
  • Placebo

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Yale University

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator