Nivolumab Combined With SOX Used in the Perioperative Treatment

Patients with unresectable factors, including unresectable tumor causes or unresectable surgical contraindications or refusal of surgery;

Previous or concurrent other malignancy;

Suffering from any chronic or major illness considered intolerable to treatment (eg, severe cardiac disease, uncontrolled hypertension, some degree of hepatic or renal dysfunction, etc.)

Patients who have previous gastrointestinal perforation, abdominal abscess or recent (within 3 months) intestinal obstruction or imaging and clinical symptoms suggestive of intestinal obstruction;