ONO-4538 Study in Patients With Richter's Transformation
ConditionRichter's Transformation
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorOno Pharmaceutical Co., Ltd.
About this trial
Investigate the efficacy and safety of ONO-4538 in patients with Richter's transformation
Eligibility criteria
Qualifiers
Histological diagnosis of diffuse large B-cell lymphoma (DLBCL)-type or Hodgkin lymphoma(HL)-type Richter's transformation with a history of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL)
In the case of DLBCL-type Richter's transformation, refractory, intolerant or ineligible for treatment of DLBCL
Patients with measurable disease
Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Disqualifiers
Serious complications
Active multiple cancers
Active central nervous system (CNS) disease
History of allogeneic hematopoietic stem cell transplantation
Trial design
Treatments tested in this trial
- ONO-4538
Treatment groups
14 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov