Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age45+
SponsorStanford University

About this trial

In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.

Eligibility criteria

Qualifiers

Undergoing trapeziectomy for thumb osteoarthritis

Disqualifiers

Pregnancy

Trial design

Treatments tested in this trial

  • NSAID capsules
  • Opioid capsule

Treatment groups

121 Participants
are divided into 2 treatment groups

Sponsors and collaborators