This is a prospective, randomized, single-blind study. Patients included in the study after successful treatment of the acute attack were randomized upon discharge from the Emergency Department into three groups: oral paracetamol-tramadol group, oral paracetamol-caffeine group and oral placebo group.
-Age > 18 years old.
Consent to participate in the study.
Pain in the flank/lumbar fossa of sudden onset with urine strips and/or imaging corresponding to the diagnosis of renal colic.
Pain score at discharge < 30 (visual analog scale - VAS or verbal numerical scale - VAS from 0 to 100).
-Inability to appreciate pain according to the VAS.
Pregnant or breastfeeding woman.
Renal insufficiency with creatinine clearance < 60 ml/min.