Study design:
A prospective phase II, non-randomized observational study of dose-escalated pencil beam proton therapy re-irradiation for pelvic recurrences from rectal cancer.
Re-irradiation is either a part of neo-adjuvant treatment or as a definitive treatment strategy for un-resectable recurrences.
• Locally recurrent rectal cancer.
Bioptically verified (adenocarcinoma )
Available dose plan from primary radiotherapy
Previous pelvic RT (>30Gy EQD2)
Non-resectable distant metastases (PET-CT)
Unable to undergo MRI, PET-CT
Inability to attend full course radiotherapy and follow up in the out patient clinic.