Perioperative Analgesia Modes in Minimally Invasive Esophagectomy

Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18-75
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

This study was designed to compare analgesic efficacy and safety of different perioperative analgesic modes in minimally invasive esophagectomy for esophageal cancer.

Eligibility criteria

Qualifiers

18-75 years;

Patients underwent laparoscopic and thoracoscopic or robotic-assisted minimally invasive esophagectomy ;

Informed consent.

Disqualifiers

Has a history of cholecystitis or urolithiasis within 3 months;

Has a history of atherothrombosis (peripheral arterial disease), stroke, myocardial infarction;

With lung diseases, such as pneumonia, atelectasis, emphysema, pulmonary bullae, etc;

Preoperative cardiac function grade ≥ III or coronary artery stenosis;

Trial design

Treatments tested in this trial

  • Preemptive flurbiprofen axetil
  • Postoperative flurbiprofen axetil
  • Patient-controlled analgesia pump

Treatment groups

102 Participants
are divided into 3 treatment groups