Phase II Clinical Study of HRS-9563 in Patients With Mild to Moderate Hypertension

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorFujian Shengdi Pharmaceutical Co., Ltd.

About this trial

This study aims to evaluate the efficacy and safety of HRS-9563 in patients with mild to moderate hypertension, and to explore its appropriate dosage.

Eligibility criteria

Qualifiers

The subject voluntarily signs the informed consent form.

Male or female, aged ≥ 18 years and ≤ 75 years;

Patients with mild to moderate hypertension;

At the Screening and Baseline periods, the mean sitting office systolic blood pressure is > 130 mmHg, and the 24-hour mean systolic blood pressure assessed by ABPM at Screening is ≥ 130 mmHg and < 160 mmHg.

Disqualifiers

Secondary hypertension;

Orthostatic hypotension;

Type 1 diabetes or poorly controlled type 2 diabetes;

Occurrence of any cardiovascular or cerebrovascular event within 6 months prior to screening;

Trial design

Treatments tested in this trial

  • HRS-9563 Injection
  • sodium chloride injection

Treatment groups

234 Participants
are divided into 4 treatment groups