Phase II Clinical Trial of PD-L1 in Combination With Vinorelbine + Cyclophosphamide + Capecitabine (VEX) Metronomic Chemotherapy With or Without Radiotherapy for Advanced Triple-negative Breast Cancer.

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

Phase II clinical trial of PD-L1 in combination with vinorelbine + cyclophosphamide + capecitabine (VEX) metronomic chemotherapy with or without radiotherapy for advanced triple-negative breast cancer.

Eligibility criteria

Qualifiers

Male or female who is 18 years of age or older on the day of signing the informed consent form.

Subjects with metastatic triple-negative breast cancer, with clear clinical data records; specific reference to the "American Society of Clinical Oncology - College of American Pathologists (ASCO/CAP) guidelines."

Have received less than or equal to 1 line of chemotherapy for metastatic breast cancer;

Have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 as assessed within 10 days before the start of study treatment;

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Adebrelimab + VEX metronomic chemotherapy + radiotherapy
  • Adebrelimab + VEX metronomic chemotherapy

Treatment groups

150 Participants
are divided into 2 treatment groups