Phase II Cohort of Spinal Stereotactic Radiotherapy in Patients Using a MR LINAC
ConditionSpinal Disease
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorM.D. Anderson Cancer Center
About this trial
To learn whether giving spinal stereotactic radiosurgery (SRSS) that uses a more advanced imaging scan method called Magnetic Resonance imaging with a Linear Accelerator (MR-LINAC) during treatment will lead to improved responses to treatment and better quality of life. SRSS is radiation therapy given to the area around your spine.
Eligibility criteria
Qualifiers
Age ≥ 18 years old
Radiographically documented disease of the spine within 4 weeks of registration (candidates with or without epidural disease allowed)
Candidate for spine SRS/SBRT as determined by treating Radiation Oncologist or Multidisciplinary Spine Conference review
Maximum of 3 contiguous vertebral levels involved with metastasis in the spine to be irradiated allowed
Disqualifiers
Patients with highly radiosensitive histologies likely to respond to conventional radiation therapy alone (ie lymphoma, multiple myeloma, etc)
Patients who are unable to undergo MRI of the spine with contrast
Patients who are pregnant
Trial design
Treatments tested in this trial
- Spine Radiosurgery
- Magnetic Resonance imaging
- MR-LINAC
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov