Phase II Study of Intensity Modulated Radiotherapy in Dose Painting for Sinus Carcinomas After Endoscopic Surgery

ConditionTumor, Solid
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorCentre Francois Baclesse

About this trial

The patient is randomized to one of the following groups:

* Experimental group: Radiotherapy in painting dose on histoscannographic mapping * Control group: standard pan-sinus radiotherapy

Eligibility criteria

Qualifiers

Patients >18 years of age

Patient with a histologically confirmed malignant tumor of the sinuses, any histological type except melanoma, lymphoma, mesenchymal tumors (sarcoma)

Patient treated by endoscopic sinonasal surgery with histosurgical mapping within 2 months prior to radiotherapy

Indication for radiotherapy treatment (photontherapy or protontherapy), without neoadjuvant chemotherapy (concomitant chemotherapy is permitted)

Disqualifiers

Patient with not operated in place tumor

Patient with distant metastases

Patient treated with neoadjuvant chemotherapy

Pregnant or breast-feeding woman or absence of contraception during genital activity

Trial design

Treatments tested in this trial

  • Radiotherapy in painting dose on histoscannographic mapping
  • Standard pan-sinusal Radiotherapy

Treatment groups

52 Participants
are divided into 2 treatment groups

Sponsors and collaborators