Pilot fMRI Studies of Aging-Related Effects of THC
ConditionTHC
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorYale University
About this trial
The purpose of this study is to begin investigating acute impairment of various forms of memory and learning by Tetrahydrocannabinol (THC) in cannabis (CNB) compared to placebo, in a 2-session per subject double-blind, random assignment, placebo-controlled counterbalanced design in young to middle-aged adults.
Eligibility criteria
Qualifiers
CNB use within past 2 years and felt "high" when used.
Able to read, speak, and understand English.
Able and willing to provide written informed consent, and willing to commit to the study protocol.
Disqualifiers
Current marijuana tolerance, desire to cut down, or cravings to use during periods of abstinence.
Positive screen for drug or alcohol (except CNB) on test day will result in rescheduling the appointment
History of adverse effects with CNB
CNB users who are abstaining
Trial design
Treatments tested in this trial
- THC
- Placebo
Treatment groups
10 Participants
are divided into 2 treatment groupsSponsors and collaborators
Yale University
Lead sponsor
Biopharmaceutical Research Company
Collaborator
Bloom Labs Cannabis Solutions
Collaborator
Source ClinicalTrials.gov