About this trial
The goal of this pilot randomized clinical trial is to learn if oral ketamine intervention can control pain in emergency department patients whose providers feel the need for additional pain medication. The main questions it aims to answer are:
* Does oral ketamine result in a different mean change in pain scores compared with oral oxycodone? * Is there a difference in the need for additional opioid administration within 24 hours after the initial dose of study medication (oral ketamine vs oral oxycodone)?
Researchers will compare oral ketamine to oral oxycodone to see if there is a difference in pain control or the need for additional opioid administration.
Participants will:
* Fill out a survey prior to study medication administration assessing pain scores, pain presentation, and medication history * Be randomized to and receive a dose of oral ketamine or oral oxycodone as the study medication for pain control * Fill out a survey assessing pain control, side effects, and safety outcomes * Receive follow-up phone calls at 1 and 3 months after enrollment to assess pain and opioid use
Eligibility criteria
Qualifiers
ED patient aged 18 years or older AND
English proficient AND
Able to give informed consent AND
Has a painful condition in the ED that includes any of the following: Musculoskeletal extremity pain, Musculoskeletal back or neck pain, Other nociceptive extremity pain
Disqualifiers
Prisoner status
Pregnant
Non-English proficient
Cannot give informed consent
Trial design
Treatments tested in this trial
- oral ketamine
- oxycodone
Treatment groups
Sponsors and collaborators
Albany Medical College
Lead sponsor
Substance Abuse and Mental Health Services Administration (SAMHSA)
Collaborator