To learn about the possible effects of a prebiotic food-enriched diet (PreFED) targeting the gut microbiome in participants with melanoma who are starting immune checkpoint blockade (ICB) therapy.
Age ≥18 years old
English-speaking
Body mass index (BMI) 18.5-45 kg/m2
Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Previous ICB treatment in the metastatic setting
History of inflammatory bowel disease, total colectomy, or bariatric surgery.
Currently taking steroids > Prednisone 10 mg/day or equivalent
Medical contraindications to the Intervention Diet as determined by the treating physician.