About this trial
The goal of this clinical trial is to see if pantoprazole (a proton pump inhibitor used for acid reflux/heart burn) can reduce nausea and vomiting after gynecologic surgery in women between the ages of 18 and 79.
Researchers will compare a placebo to the active medication.
Participants will be asked to take three pills around their surgery, two taken before and one taken the night after.
Eligibility criteria
Qualifiers
Undergoing elective gynecological surgery by either an open abdominal or minimally invasive approach (to include both endoscopic and vaginal). Procedure must be performed under general anesthesia.
Disqualifiers
Pregnant,
Patients with gastrointestinal disease requiring ongoing medical management.
Prior gastrointestinal surgery with the exception of diagnostic procedures, appendectomy and cholecystectomy.
Patients with a history of H2 receptor blocker use, proton pump inhibitor use or other GERD specific therapy within 30 days of surgery.
Trial design
Treatments tested in this trial
- pantoprazole
- Placebo