Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age40-80
SponsorUniversity of British Columbia
About this trial
This study evaluates the use of an oral multi-strain probiotic in the treatment of depression in individuals with Parkinson's Disease. Participants will be randomized to either a 12-week multi-strain probiotic treatment or placebo intervention.
Eligibility criteria
Qualifiers
Confirmed diagnosis of Parkinson's disease based on UK Brain Bank criteria
Between the ages of 40-80 years
Mild to Moderate PD (Hoehn and Yahr stage between 1-3 in the "ON" state)
Mild to moderate depression (BDI-II score of 14-28 in the "ON" state)
Disqualifiers
Atypical Parkinsonism
Active suicidality
Active psychosis
Cognitive score (MoCA) of < 21 in the "ON" state
Trial design
Treatments tested in this trial
- Probiotic
- Placebo
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov