About this trial
The purpose of this study is to learn if giving 17-hydroxyprogesterone caproate (17 OHPC) to mothers with preeclampsia diagnosed before 34 weeks gestation improves mother and baby outcomes.
Eligibility criteria
Qualifiers
UMMC antepartum patients with preterm PE between 23 0/7ths and 34 0/7ths weeks gestation when initially evaluated
Willing and able to understand study procedures and to provide informed consent
Disqualifiers
>33 weeks gestational age or <23 weeks gestation
Maternal compromise requiring emergent delivery (ongoing placental abruption, DIC, pulmonary edema).
Fetal compromise requiring emergent delivery (fetal bradycardia, recurrent late fetal heart rate decelerations, minimal to absent fetal heart rate variability).
Preterm premature rupture of membranes (PPROM) > 34 weeks gestation;
Trial design
Treatments tested in this trial
- 17 OHPC