Promoting Recovery After STroke With Amantadine
Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-85
SponsorUniversity of Pennsylvania
About this trial
The investigators aim to examine whether amantadine can help patients recover from stroke. This will be a blinded randomized clinical trial (RCT). Patients will be randomized post-ischemic or hemorrhagic stroke either to the placebo arm or amantadine arm. Patients will be on study drug or placebo for 1 month but will be enrolled for 3 months total. At various time points patients will be examined and fill out questionnaires to determine level of stroke recovery.
Eligibility criteria
Qualifiers
18 to 85 years old, male and female
Modified Rankin Score (mRS)<=2 prior to stroke
Ischemic or hemorrhagic stroke as diagnosed by vascular neurologist or as proven on magnetic resonance imaging (MRI) or non-contrast head computed tomography NCHCT)
24 hours to 3 weeks after stroke onset or time last known well prior to detection of symptoms
Disqualifiers
Any degree of receptive aphasia
Moderate or severe expressive aphasia
Currently pregnant or plans to get pregnant
Currently breastfeeding
Trial design
Treatments tested in this trial
- Amantadine
- Placebo
Treatment groups
60 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov