Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexFemale
Age18+
SponsorUniversity of Michigan

About this trial

This research study is being done to learn what effect a single dose of calcium gluconate will have on blood loss at the time of cesarean delivery in pregnancy patients at high risk for uterine atony.

Eligibility criteria

Qualifiers

English speaking

Viable Intrauterine Pregnancy, Gestational Age ≥24 weeks

Labor Converted to Cesarean Delivery at High Risk for Atonic Bleeding Defined as: Any exposure to oxytocin infusion for labor augmentation or induction prior to cesarean delivery

> 4 Prior deliveries

Disqualifiers

Non-English speaking

Antenatal suspicion for placenta accreta spectrum

History of allergic reaction to Calcium Gluconate

Patients with hypertensive disorder of pregnancy receiving Magnesium Sulfate for seizure prophylaxis

Trial design

Treatments tested in this trial

  • Calcium Gluconate
  • Saline

Treatment groups

140 Participants
are divided into 2 treatment groups

Sponsors and collaborators