The goal of this clinical trial is to evaluate the efficacy of propolis in the prevention of oral mucositis and reducing pain score in children undergoing chemotherapy, and assessing its impact on body mass index, pediatric quality of life and total antioxidant assay. The main question it aims to answer is:
What is the effect of propolis on oral mucositis scores in children undergoing chemotherapy?
Participants will:
Take propolis 3 times daily for 21 days follow up weekly for 3 weeks
Children of both genders less than 18 years receiving intensive chemotherapy.
Taking intensified chemotherapy
A healthy oral mucosa.
Allergy to bee products.
Severe systemic illness unrelated to cancer (Diabetes, Hypertension, …)
Inability to take oral medication or unwillingness to participate in the study
Radiotherapy in the head and neck area.