About this trial
A multicenter prospective phase II study of rituximab combined, lenalidomide, dexamethasone followed by lenalidomide maintenance in patients with newly diagnosed Waldenström's macroglobulinemia (Ballondor trial)
Eligibility criteria
Qualifiers
Clinicopathological diagnosis of Waldenstrom's Macroglobulinemia
Patients who meet criteria for treatment using consensus panel criteria from the Second International Workshop on Waldenstrom's macroglobulinemia
Male or female patients aged ≥19 years
Eastern Cooperative Oncology Group (ECOG) performance status 0-2
Disqualifiers
Central nervous system involvement central nervous system (CNS) involvement by Waldenström's macroglobulinemia
Patients who have received rituximab, lenalidomide, or bortezomib
Patients who are allergic or hypersensitive to mouse (murine), chimeric, human or humanized proteins, lenalidomide, bortezomib
Absolute neutrophil count (ANC) <1,000 / μL
Trial design
Treatments tested in this trial
- Lenalidomide, Bortezomib, Rituximab, Dexamethasone