About this trial
The purpose of this research is to determine whether bladder cancer monitoring can be improved by replacing some cystoscopy procedures with urine testing. Specifically, this study examines whether there are any differences in urinary symptoms, discomfort, number of invasive procedures, anxiety, complications, cancer recurrence or cancer progression when some cystoscopy procedures are replaced with urine testing.
Eligibility criteria
Qualifiers
Aged 18 years or older
multifocal low grade non-invasive urothelial carcinoma of any size
solitary low grade non-invasive urothelial carcinoma greater than 3cm in size
recurrent low grade non-invasive urothelial carcinoma
Disqualifiers
History of total cystectomy of the bladder.
History of urinary diversion (e.g., neo-bladder, colon pouch, or ileal conduit).
History of muscle-invasive bladder tumor.
Pregnancy or lactation.
Trial design
Treatments tested in this trial
- Cystoscopy
- Bladder EpiCheck urine test
- Xpert Bladder Cancer Monitor urine test
Treatment groups
Sponsors and collaborators
White River Junction Veterans Affairs Medical Center
Lead sponsor
National Cancer Institute (NCI)
Collaborator
University of Texas Southwestern Medical Center
Collaborator
Medical University of South Carolina
Collaborator