SURF is a randomised controlled, parallel group, single blind phase II study designed to assess the safety and potential efficacy of an innovative therapeutic strategy for urethral stenosis based on adjuvant injection of autologous Adipose-Derived Stromal Vascular Fraction of Adipose Tissue (ADSVF) during endoscopic urethrotomy (standard care).
Signed informed consent
Male, aged from 18 to 85 years
Bulbar urethral stenosis ≤ 3 cm.
At least one urethral dilatation or urethrotomy for the bulbar stenosis in the past 24 months before diagnosis of stenosis
Urethral stenosis of other location than bulbar
Urethral stenosis length > 3 cm
Urethral stenosis on reconstructed penis (transgender, post amputation)
Prior perineal or pelvic radiotherapy