Safety of Dose Escalation in Definitive Hypofractionated Radiation Therapy and Hormone Therapy With SpaceOAR TM for Patients With High - Risk Localized Prostate Cancer (DESAR-H)

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexMale
Age20+
SponsorSamsung Medical Center

About this trial

Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients who underwent low-fractionation curative radiation therapy and hormone therapy

Eligibility criteria

Qualifiers

Histopathologically confirmed prostate adenocarcinoma within 6 months of study enrollment

Patients with prostate cancer at high risk or above (c T3a-T4 or grade group 4-5 or PSA > 20 n g/mL) )

Patients who have undergone or are scheduled to undergo hormone therapy for high-risk prostate cancer

Adults over 20 years of age

Disqualifiers

prostate removal surgery, Patients with a history of lower pelvic surgery including rectal cancer surgery

primary cancer Patients with posterior extracapsular extension

Medically biodegradable substances such as bleeding predisposition Patients for whom infusion is not appropriate

Patients with a history of previous pelvic radiation therapy

Trial design

Treatments tested in this trial

  • Dose increase after injection of biodegradable material A safety study of high-risk prostate cancer patients

Treatment groups

33 Participants
are divided into 1 treatment group

Sponsors and collaborators