This research study is testing the effectiveness and safety of semaglutide (Wegovy) in people with trichotillomania, also known as hair-pulling disorder.
Men and women age 18-75;
Diagnosis of current trichotillomania based on DSM-5 criteria and confirmed using the clinician-administered MIDI (13);
Hair pulling daily with urges to pull as the trigger in >50% of the episodes of pulling;
Women of childbearing age are required to have a negative result on a beta-human chorionic gonadotropin pregnancy test;
Infrequent pulling (i.e. less than daily) or automatic pulling (i.e. no urges to pull);
Unstable medical illness or clinically significant abnormalities on laboratory tests, EKG, or physical examination at screen as determined by the investigator;
History of seizures;
Myocardial infarction within 6 months;