About this trial
Shoulder tendon tears are a common cause of shoulder pain and disability and after surgery the repaired tendon often does not heal. In this pilot study, men with low sex hormone levels will be randomly assigned to receive sex hormone therapy or placebo pills while healing from tendon repair surgery in their shoulder. Sex hormone therapy increases sex hormone levels, and the investigators will test whether these increased sex hormone levels show promise in improving tendon healing and patient shoulder function and pain.
Eligibility criteria
Qualifiers
A plan for a primary rotator cuff repair
Male sex
>1 cm tear width, full thickness supraspinatus/infraspinatus tear
Disqualifiers
Active infection
Pre-operative testosterone supplementation
Known diagnosis of secondary testicular failure or testosterone deficiency
Medically unfit for operative intervention
Trial design
Treatments tested in this trial
- Clomiphene Citrate
- Rotator Cuff Repair