The study is designed to diminish intra-dialytic hypertension in chrnic hemodialysis patients suffering from metabolic acidosis (low bicarbonate levels). The intervention is a tab of 500 mg sodium bicarbonate twice a day for one month, vs. placebo.
Chronic hemodialysis patient > 3 months
3 dialysis per week, KTV>1.2
capable of informed concent.
rise in blood pressure during hemodialysis > 10 mm Hg, for at least 50% of dialysis sessions in the month prior to inclusion.
age under 18,
pregnancy
unable to sign informed concent
planned for kidney transplant in the following 3 month.