Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorTianjin Medical University Cancer Institute and Hospital

About this trial

A phase II clinical trial of stereotactic radiosurgery versus radiofrequency ablation in the treatment of inoperable primary liver cancer in specific sites

Eligibility criteria

Qualifiers

Prior to implementing any trial-related procedures, written informed consent must be signed;

Age ≥ 18 years and ≤ 75 years;

Child-Pugh score ≤ 7;KPS score ≥ 70;

The patient must be clearly diagnosed with hepatocellular carcinoma, usually confirmed through imaging (CT, MRI) or histological examination (biopsy);

Disqualifiers

Possible surgical intervention;

Presence of other serious comorbidities, such as uncontrolled cardiovascular diseases, pulmonary diseases, or dysfunction of other organs, where the overall health status is poor and may result in treatment intolerance;

Severe liver dysfunction exceeding the specific criteria defined in the trial;

Other malignancies diagnosed within 5 years prior to the first treatment or at the time of diagnosis of hepatocellular carcinoma;

Trial design

Treatments tested in this trial

  • Stereotactic Body Radiation Therapy (SBRT)
  • Radiofrequency ablation therapy

Treatment groups

130 Participants
are divided into 2 treatment groups