Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology
ConditionDyspnea
Trial statusRecruiting
Trial phasePhase 2, Phase 3
Trial typeInterventional
Biological sexAll
Age18+
SponsorM.D. Anderson Cancer Center
About this trial
To learn about the effect of Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology (SPOT-ON) treatment on the severity of shortness of breath in patients with cancer.
Eligibility criteria
Qualifiers
Diagnosis of cancer
Age 18 or older.
Admitted to a medical floor.
Dyspnea intensity at rest of at least 4 on a 0-10-point NRS (where 0 = none, 10 = worst).
Disqualifiers
Hemodynamic instability requiring active Merit Team or ICU team involvement.
Delirium as per clinical team's assessment in the Electronic Health Record (EHR).
Severe hypoxemia (SpO2 < 90% despite supplemental oxygen of up to 6 L/min).
Continuous positive airway pressure (CPAP) use for obstructive sleep apnea, actively using >10 hours a day.
Trial design
Treatments tested in this trial
- SPOT-ON Early Start
- SPOT-ON Delayed Start
Treatment groups
150 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov