About this trial
Evaluating the efficacy and safety of PD-L1 (Programmed Death-L1)antibody combined with endoscopy and radiotherapy for inoperable cT1b-2 (clinical stage tumor 1b-2) esophageal squamous cell carcinoma
Eligibility criteria
Qualifiers
Signed written informed consent to voluntarily enroll in the study
Age 18-75 years
Histologically or cytologically confirmed squamous esophageal cancer of the thoracic segment
Staging of clinical tumor stage T1b-2N0M0 (according to American Joint Committee on Cancer 8th edition) as judged by the investigator
Disqualifiers
Tumour-related criteria Patients with non-squamous oesophageal cancer Staging not consistent with clinical tumor stage T1b~2N0M0 Other malignancies diagnosed within 5 years prior to first use of study drug, except cured carcinoma in situ of the uterine cervix, basal or squamous cell skin cancers, limited prostate cancer treated with radical surgery, and ductal carcinoma in situ treated with radical surgery
New York Heart Association class 2 or higher heart failure;
unstable angina pectoris;
myocardial infarction within 1 year;
Trial design
Treatments tested in this trial
- Adebrelimab injection
- Albumin-Bound Paclitaxel
- Carboplatin injection