Study of Dextromethorphan in OCD and Related Disorders

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorStanford University

About this trial

The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.

Eligibility criteria

Qualifiers

Diagnosis of obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), illness anxiety disorder (IAD) or somatic symptom disorder (SSD)

Living within California

Capacity to provide informed consent

Disqualifiers

Current bipolar disorder or psychotic disorder

Active moderate or severe substance use disorder, lifetime severe substance use disorder

Pregnant or nursing women

Use of prescribed psychotropic medications other than fluoxetine for 2 weeks prior to study start

Trial design

Treatments tested in this trial

  • Fluoxetine
  • Dextromethorphan

Treatment groups

60 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Stanford University

Lead sponsor

Avy L. & Roberta L. Miller Foundation

Collaborator