About this trial
ADRIATIC study explored the benefits of immune maintenance therapy after LS-SCLC radiotherapy and chemotherapy. In the presence of immunotherapy, is it necessary to increase the dosage of radiotherapy and can it further improve the efficacy? This study aims to explore the efficacy and safety of simultaneous integrated boost hyperfractionation radiotherapy combined with probiotics and Adalberg monoclonal antibody consolidation therapy for small cell lung cancer.
Eligibility criteria
Qualifiers
Sign written informed consent before implementing any experimental procedures;
Age range: 18-80 years old;
Pathological diagnosis of small cell lung cancer;
Limited stage;
Disqualifiers
Progress after 2 induction treatments;
Severe emphysema, interstitial changes in the lungs, COPD patients;
Resting blood oxygen<93;
Have a history of other malignant tumors and have received chemotherapy in the past 3 years;
Trial design
Treatments tested in this trial
- Probiotics
- concurrent Hyperfractionated Radiotherapy
- Immunotherapy