Study of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML Patients

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-65
SponsorThe First Affiliated Hospital of Soochow University

About this trial

The purpose of this study is to evaluate the efficacy and safety of VA combined with HAAG in the induction treatment of newly diagnosed acute myeloid leukemia.

Eligibility criteria

Qualifiers

Newly diagnosed intermediate and high-risk AML according to the WHO (2022) classification of acute myeloid leukemia (non-APL).

Age 18-65.

ECOG score: 0-2.

No history of previous chemotherapy or target therapy.

Disqualifiers

AML transformed with chronic myelogenous leukemia.

Acute promyelocytic leukemia (type M3).

Patients with a second malignancy requiring treatment.

Patients with uncontrolled active infection.

Trial design

Treatments tested in this trial

  • venetoclax, azacitidine and HAAG regimen

Treatment groups

60 Participants
are divided into 1 treatment group