Study of ZG005 in Combination With Platinum-Based Chemotherapy in Participants With Advanced Biliary Tract Carcinoma

Trial statusRecruiting
Trial phasePhase 2
Trial typeInterventional
Biological sexAll
Age18-75
SponsorSuzhou Zelgen Biopharmaceuticals Co.,Ltd

About this trial

This is a randomized, open-label, phase II study evaluating first-line treatment for advanced gallbladder cancer. It aims to assess the efficacy, safety, pharmacokinetics, and immunogenicity of the ZG005 in Combination with gemcitabine and cisplatin as first-line therapy in Participants with advanced gallbladder cancer.

Eligibility criteria

Qualifiers

Fully understand the study and voluntarily sign the informed consent form.

Subjects with a histopathological or cytologically diagnosis of Gallbladder cancer.

Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1.

Life expectancy of at least 3 months.

Disqualifiers

Participants were deemed unsuitable for participating in the study by the investigator for any reasons.

Trial design

Treatments tested in this trial

  • ZG005
  • Tislelizumab
  • Gemcitabine
  • Cisplatin

Treatment groups

60 Participants
are divided into 2 treatment groups