About this trial
This study aims to evaluete of tthe efficacy and safety of using different doses of the drug Grammidin with anesthetic, a metered dose topical spray, in the treatment of acute infectious and inflammatory pharyngeal diseases.
Eligibility criteria
Qualifiers
Male or female patients aged 18 to 75 years inclusive.
Unpleasant sensations/discomfort in the throat - symptoms of pharyngeal paresthesia (scratchy throat, dryness or sore sensation ("foreign body" sensation));
Painful sensations in the throat, including sore throat at rest, throat burning, or pain upon swallowing saliva;
Severity of the symptom "sore throat" from 55 mm to 80 mm on the Visual Analog Scale (VAS).
Disqualifiers
Erroneous inclusion of a patient in the study (not meeting inclusion/exclusion criteria at the time of randomization).
Ineffectiveness of therapy. Therapy will be considered ineffective if there is no clinical improvement by Visit 2 (Day 3-4 of therapy) - persistence or worsening of the symptom "sore throat" and catarrhal phenomena compared to baseline data. If excluded, the patient will be assigned alternative treatment at the discretion of the investigator.
Patient non-compliance (a patient is considered compliant if the number of applications of the study drug/comparison drug is not less than 17 and not more than 25).
Smoking more than 10 cigarettes per day.
Trial design
Treatments tested in this trial
- Grammidin with anesthetic
- Septolete Total